Tax-loss harvesting alternatives for AMGN

Among the 28 Biotechnology peers screened, VRTX (Vertex Pharmaceuticals) has tracked AMGN most closely over the past year, with a return correlation of 0.53. The strongest fund stand-in is PPH (VanEck Pharma ETF) at 0.69 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
VRTX	Vertex Pharmaceuticals	Biotechnology	0.53	0.39	0.38	0.44
GILD	Gilead Sciences	Biotechnology	0.49	0.42	0.45	0.49
BIIB	Biogen Inc.	Biotechnology	0.48	0.51	0.41	0.40
INCY	Incyte	Biotechnology	0.47	0.39	0.35	0.38
REGN	Regeneron Pharmaceuticals	Biotechnology	0.46	0.41	0.39	0.44
EXEL	Exelixis	Biotechnology	0.38	0.21	0.22	0.30
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.35	0.31	0.25	0.28
HALO	Halozyme	Biotechnology	0.35	0.31	0.29	0.32
VIR	Vir Biotechnology, Inc.	Biotechnology	0.29	0.27	0.22	0.12
FTRE	Fortrea	Biotechnology	0.28	0.27	0.27	—
BMRN	BioMarin Pharmaceutical	Biotechnology	0.28	0.32	0.28	0.37
NBIX	Neurocrine Biosciences	Biotechnology	0.27	0.24	0.22	0.29
XNCR	Xencor Inc	Biotechnology	0.26	0.27	0.29	0.33
RCUS	Arcus Biosciences, Inc.	Biotechnology	0.25	0.25	0.20	0.23
SRPT	Sarepta Therapeutics	Biotechnology	0.25	0.20	0.20	0.24
VCEL	Vericel	Biotechnology	0.24	0.26	0.22	0.22
MRNA	Moderna Inc.	Biotechnology	0.22	0.21	0.20	0.17
TGTX	TG Therapeutics, Inc.	Biotechnology	0.22	0.20	0.14	0.21
ADMA	ADMA Biologics, Inc.	Biotechnology	0.20	0.18	0.17	0.13
CYTK	Cytokinetics	Biotechnology	0.19	0.18	0.17	0.24
RGEN	Repligen	Biotechnology	0.19	0.22	0.18	0.26
ARWR	Arrowhead Pharmaceuticals	Biotechnology	0.18	0.23	0.22	0.23
LGND	Ligand Pharmaceuticals, Inc.	Biotechnology	0.18	0.17	0.17	0.28
KRYS	Krystal Biotech	Biotechnology	0.18	0.20	0.15	0.20
UTHR	United Therapeutics	Biotechnology	0.17	0.24	0.26	0.30
PTGX	Protagonist Therapeutics, Inc.	Biotechnology	0.14	0.19	0.09	0.10
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.11	0.15	0.16	0.16
ROIV	Roivant Sciences	Biotechnology	0.07	0.19	0.11	—

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.69	0.62	0.58	0.63
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.68	0.64	0.59	0.66
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.68	0.64	0.60	0.67
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.67	0.64	0.58	0.66
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.67	0.64	0.58	0.66
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.63	0.58	0.55	0.61
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.61	0.61	0.53	0.60
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.42	0.43	0.35	0.44
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.38	0.45	0.42	0.51
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.35	0.35	0.33	0.46
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.24	0.30	0.26	0.34
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.19	0.28	0.33	0.45

NEXT STEPS

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Replacement research for AMGN's peers

VRTX GILD BIIB INCY REGN EXEL ALNY HALO VIR FTRE BMRN NBIX XNCR RCUS SRPT VCEL MRNA TGTX ADMA CYTK RGEN ARWR LGND KRYS UTHR PTGX HRMY ROIV

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.