Tax-loss harvesting alternatives for EXEL

Among the 28 Biotechnology peers screened, INCY (Incyte) has tracked EXEL most closely over the past year, with a return correlation of 0.49. The strongest fund stand-in is IBB (iShares Biotechnology ETF) at 0.51 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
INCY	Incyte	Biotechnology	0.49	0.28	0.30	0.40
NBIX	Neurocrine Biosciences	Biotechnology	0.46	0.30	0.33	0.38
AMGN	Amgen Inc.	Biotechnology	0.38	0.21	0.22	0.30
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.35	0.12	0.19	0.16
REGN	Regeneron Pharmaceuticals	Biotechnology	0.33	0.24	0.24	0.33
VRTX	Vertex Pharmaceuticals	Biotechnology	0.33	0.20	0.23	0.34
TGTX	TG Therapeutics, Inc.	Biotechnology	0.32	0.20	0.25	0.25
HALO	Halozyme	Biotechnology	0.31	0.20	0.26	0.35
GILD	Gilead Sciences	Biotechnology	0.29	0.21	0.21	0.24
SRPT	Sarepta Therapeutics	Biotechnology	0.28	0.15	0.19	0.26
BIIB	Biogen Inc.	Biotechnology	0.28	0.22	0.25	0.26
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.27	0.19	0.21	0.33
VIR	Vir Biotechnology, Inc.	Biotechnology	0.26	0.19	0.18	0.13
BMRN	BioMarin Pharmaceutical	Biotechnology	0.25	0.17	0.25	0.34
ROIV	Roivant Sciences	Biotechnology	0.25	0.25	0.21	—
XNCR	Xencor Inc	Biotechnology	0.24	0.18	0.24	0.33
LGND	Ligand Pharmaceuticals, Inc.	Biotechnology	0.24	0.18	0.25	0.29
KRYS	Krystal Biotech	Biotechnology	0.23	0.21	0.19	0.20
CYTK	Cytokinetics	Biotechnology	0.22	0.12	0.19	0.24
RGEN	Repligen	Biotechnology	0.22	0.16	0.21	0.26
VCEL	Vericel	Biotechnology	0.22	0.17	0.24	0.23
RCUS	Arcus Biosciences, Inc.	Biotechnology	0.20	0.21	0.24	0.26
PTGX	Protagonist Therapeutics, Inc.	Biotechnology	0.19	0.17	0.21	0.16
FTRE	Fortrea	Biotechnology	0.19	0.14	0.14	—
ARWR	Arrowhead Pharmaceuticals	Biotechnology	0.18	0.17	0.25	0.25
MRNA	Moderna Inc.	Biotechnology	0.17	0.14	0.15	0.13
UTHR	United Therapeutics	Biotechnology	0.16	0.14	0.16	0.27
ADMA	ADMA Biologics, Inc.	Biotechnology	0.11	0.12	0.18	0.18

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.51	0.37	0.42	0.51
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.46	0.35	0.42	0.53
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.40	0.29	0.35	0.42
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.40	0.29	0.34	0.42
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.39	0.28	0.33	0.40
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.38	0.28	0.33	0.43
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.36	0.26	0.30	0.38
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.35	0.31	0.38	0.45
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.34	0.26	0.31	0.39
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.28	0.23	0.31	0.38
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.23	0.17	0.23	0.32
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.14	0.17	0.26	0.32

NEXT STEPS

Harvesting a loss in EXEL?

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Replacement research for EXEL's peers

INCY NBIX AMGN HRMY REGN VRTX TGTX HALO GILD SRPT BIIB ALNY VIR BMRN ROIV XNCR LGND KRYS CYTK RGEN VCEL RCUS PTGX FTRE ARWR MRNA UTHR ADMA

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.