Tax-loss harvesting alternatives for TGTX

Among the 28 Biotechnology peers screened, KRYS (Krystal Biotech) has tracked TGTX most closely over the past year, with a return correlation of 0.35. The strongest fund stand-in is XBI (SPDR S&P Biotech ETF) at 0.50 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
KRYS	Krystal Biotech	Biotechnology	0.35	0.30	0.24	0.25
NBIX	Neurocrine Biosciences	Biotechnology	0.33	0.20	0.21	0.23
XNCR	Xencor Inc	Biotechnology	0.33	0.26	0.30	0.29
EXEL	Exelixis	Biotechnology	0.30	0.20	0.25	0.25
INCY	Incyte	Biotechnology	0.29	0.23	0.23	0.23
VCEL	Vericel	Biotechnology	0.27	0.22	0.38	0.28
VIR	Vir Biotechnology, Inc.	Biotechnology	0.26	0.23	0.19	0.12
ARWR	Arrowhead Pharmaceuticals	Biotechnology	0.26	0.28	0.39	0.29
ROIV	Roivant Sciences	Biotechnology	0.24	0.26	0.24	—
SRPT	Sarepta Therapeutics	Biotechnology	0.24	0.18	0.19	0.20
HALO	Halozyme	Biotechnology	0.23	0.20	0.25	0.28
REGN	Regeneron Pharmaceuticals	Biotechnology	0.23	0.17	0.16	0.20
PTGX	Protagonist Therapeutics, Inc.	Biotechnology	0.21	0.25	0.25	0.18
RCUS	Arcus Biosciences, Inc.	Biotechnology	0.21	0.22	0.31	0.28
VRTX	Vertex Pharmaceuticals	Biotechnology	0.21	0.19	0.21	0.24
FTRE	Fortrea	Biotechnology	0.21	0.09	0.07	—
BMRN	BioMarin Pharmaceutical	Biotechnology	0.20	0.23	0.26	0.26
AMGN	Amgen Inc.	Biotechnology	0.19	0.18	0.14	0.21
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.18	0.24	0.27	—
CYTK	Cytokinetics	Biotechnology	0.18	0.16	0.24	0.24
BIIB	Biogen Inc.	Biotechnology	0.17	0.17	0.22	0.19
MRNA	Moderna Inc.	Biotechnology	0.17	0.17	0.17	0.16
GILD	Gilead Sciences	Biotechnology	0.16	0.14	0.17	0.18
LGND	Ligand Pharmaceuticals, Inc.	Biotechnology	0.15	0.22	0.30	0.30
RGEN	Repligen	Biotechnology	0.15	0.19	0.27	0.27
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.12	0.16	0.24	0.24
ADMA	ADMA Biologics, Inc.	Biotechnology	0.10	0.22	0.34	0.22
UTHR	United Therapeutics	Biotechnology	0.06	0.16	0.13	0.17

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.50	0.46	0.56	0.51
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.45	0.37	0.43	0.42
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.45	0.39	0.46	0.44
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.33	0.35	0.47	0.45
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.31	0.26	0.28	0.33
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.29	0.27	0.34	0.36
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.28	0.26	0.34	0.36
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.25	0.24	0.31	0.33
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.22	0.22	0.28	0.30
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.19	0.20	0.24	0.29
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.18	0.14	0.24	0.27
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.12	0.19	0.33	0.34

NEXT STEPS

Harvesting a loss in TGTX?

Estimate what the harvest could save →Check the eight wash-sale traps →Document the trade with a Tax Memo →

Replacement research for TGTX's peers

KRYS NBIX XNCR EXEL INCY VCEL VIR ARWR ROIV SRPT HALO REGN PTGX RCUS VRTX FTRE BMRN AMGN HRMY CYTK BIIB MRNA GILD LGND RGEN ALNY ADMA UTHR

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.