Tax-loss harvesting alternatives for ARWR

Among the 28 Biotechnology peers screened, CYTK (Cytokinetics) has tracked ARWR most closely over the past year, with a return correlation of 0.38. The strongest fund stand-in is XBI (SPDR S&P Biotech ETF) at 0.48 over the past year. Correlations are computed from daily closing-price returns aligned by trading day.

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STOCKS

Single-name peers

Ticker	Name	Sub-industry	1Y	3Y	5Y	10Y
CYTK	Cytokinetics	Biotechnology	0.38	0.27	0.33	0.27
SRPT	Sarepta Therapeutics	Biotechnology	0.36	0.33	0.34	0.27
VIR	Vir Biotechnology, Inc.	Biotechnology	0.35	0.35	0.33	0.22
RCUS	Arcus Biosciences, Inc.	Biotechnology	0.34	0.34	0.39	0.30
FTRE	Fortrea	Biotechnology	0.30	0.27	0.26	—
XNCR	Xencor Inc	Biotechnology	0.29	0.34	0.39	0.34
NBIX	Neurocrine Biosciences	Biotechnology	0.27	0.24	0.29	0.29
UTHR	United Therapeutics	Biotechnology	0.27	0.23	0.23	0.21
TGTX	TG Therapeutics, Inc.	Biotechnology	0.26	0.28	0.39	0.29
KRYS	Krystal Biotech	Biotechnology	0.25	0.26	0.27	0.28
LGND	Ligand Pharmaceuticals, Inc.	Biotechnology	0.25	0.28	0.35	0.32
ROIV	Roivant Sciences	Biotechnology	0.24	0.32	0.28	—
VRTX	Vertex Pharmaceuticals	Biotechnology	0.22	0.25	0.28	0.26
PTGX	Protagonist Therapeutics, Inc.	Biotechnology	0.18	0.19	0.23	0.14
BIIB	Biogen Inc.	Biotechnology	0.17	0.30	0.33	0.23
BMRN	BioMarin Pharmaceutical	Biotechnology	0.17	0.28	0.35	0.29
RGEN	Repligen	Biotechnology	0.17	0.32	0.36	0.30
GILD	Gilead Sciences	Biotechnology	0.16	0.19	0.24	0.19
EXEL	Exelixis	Biotechnology	0.16	0.17	0.25	0.24
HALO	Halozyme	Biotechnology	0.15	0.21	0.28	0.25
ALNY	Alnylam Pharmaceuticals	Biotechnology	0.14	0.24	0.33	0.28
INCY	Incyte	Biotechnology	0.14	0.24	0.29	0.26
AMGN	Amgen Inc.	Biotechnology	0.14	0.23	0.22	0.23
HRMY	Harmony Biosciences Holdings, Inc.	Biotechnology	0.13	0.20	0.29	—
ADMA	ADMA Biologics, Inc.	Biotechnology	0.13	0.17	0.29	0.22
MRNA	Moderna Inc.	Biotechnology	0.12	0.19	0.23	0.19
VCEL	Vericel	Biotechnology	0.11	0.25	0.38	0.30
REGN	Regeneron Pharmaceuticals	Biotechnology	0.11	0.24	0.26	0.22

ETFS

Fund stand-ins

An ETF is generally not 'substantially identical' to a single stock, which is why funds are the standard wash-sale-aware replacement.

Ticker	Name	Focus	Match	1Y	3Y	5Y	10Y
XBI	SPDR S&P Biotech ETF	Biotechnology (Equal Wt)	INDUSTRY	0.48	0.57	0.66	0.55
XPH	SPDR S&P Pharmaceuticals	Pharmaceuticals (Equal Wt)	INDUSTRY	0.42	0.48	0.53	0.43
IBB	iShares Biotechnology ETF	Biotechnology	INDUSTRY	0.42	0.53	0.60	0.49
ARKG	ARK Genomic Revolution ETF	Genomics (Active)	INDUSTRY	0.35	0.47	0.55	0.48
IHE	iShares US Pharmaceuticals ETF	Pharmaceuticals	INDUSTRY	0.29	0.36	0.40	0.36
FHLC	Fidelity MSCI Health Care ETF	Health Care Sector	SECTOR	0.25	0.37	0.44	0.39
VHT	Vanguard Health Care ETF	Health Care Sector	SECTOR	0.25	0.37	0.44	0.39
IYH	iShares US Healthcare ETF	Health Care Sector	SECTOR	0.23	0.34	0.41	0.36
PPH	VanEck Pharma ETF	Pharmaceuticals	INDUSTRY	0.21	0.29	0.34	0.31
XLV	Health Care Select Sector SPDR	Health Care Sector	SECTOR	0.19	0.31	0.37	0.33
IHF	iShares Health Care Providers	Health Care Providers	INDUSTRY	0.13	0.17	0.27	0.30
IHI	iShares Medical Devices ETF	Medical Devices	SUB-IND	0.09	0.25	0.37	0.36

NEXT STEPS

Harvesting a loss in ARWR?

Estimate what the harvest could save →Check the eight wash-sale traps →Document the trade with a Tax Memo →

Replacement research for ARWR's peers

CYTK SRPT VIR RCUS FTRE XNCR NBIX UTHR TGTX KRYS LGND ROIV VRTX PTGX BIIB BMRN RGEN GILD EXEL HALO ALNY INCY AMGN HRMY ADMA MRNA VCEL REGN

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Method: Pearson correlation of daily closing-price returns, Yahoo Finance data, series aligned by trading day, refreshed weekly. A cell is blank when overlapping history covers less than 60% of its window. Correlation is descriptive, not predictive. Wash-sale treatment depends on facts and circumstances — confirm with a tax professional. Not investment advice.